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If managing your pain becomes harder and harder, you are not alone. Approximately one in five Americans suffers from chronic pain on a regular basis, facing limited treatment options for pain management; contrast delta8painrelief. Delta-10 reduces anxiety, fights nausea, diminishes pain, is a minor cannabinoid, and is less psychoactive than delta-9 THC. It does carry a high probability of failing a drug test. An analogue of tetrahydrocannabinol (THC) with antiemetic, anxiolytic, appetite-stimulating, analgesic, and neuroprotective properties. Delta-10-tetrahydrocannabinol (delta-10-THC) binds to the cannabinoid G-protein coupled receptor CB1, located in the central nervous system; CB1 receptor activation inhibits adenyl cyclase, increases mitogen-activated protein kinase activities, modulates several potassium channel conductances and inhibits N- and P/Q-type Ca2+ channels. This agent exhibits a lower psychotropic potency than delta-9-tetrahydrocannabinol (delta-9-THC), the primary form of THC found in cannabis. [from NCI *]> * NCI Thesaurus (NCIt) provides reference terminology for many NCI and other systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities. |